Valproic acid (VPA) is one of the Bench most frequently used antiepileptic drugs for the treatment of focal and generalized epilepsies, absence seizures, and Lennox-Gastaut syndrome (LGS).VPA has been demonstrated to have a negative effect on both the intrinsic and extrinsic coagulation systems and controversy exists about the clinical relevance of such hematological abnormalities.We describe a case of reversible Ice Bucket lung hemorrage due to VPA.In English-language literature only two other similar cases (one of which fatal) have been described so far.